Recent studies have shown that the longer the breastfeeding time (the longest feeding time is one year), the greater the beneficial effect on infant intelligence.
On July 29, according to an online survey published in the Journal of the American Medical Association, Pediatrics, the IQ of children who had been breast-feeding for the first year of their lives increased by 4 points compared with infants whose breast-feeding time was shorter. At the age of three, these children showed a better ability to understand and accept, and at the age of seven, they had higher linguistic and nonverbal intelligence. The authors of the study stated that “both domestic and international advocates for breast-feeding babies for the first six months of their lives, supplementing with complementary foods and continuing breast-feeding until one year old. Our findings provide more support for this recommendation.â€
The research team led by Dr. Mandy Belfort, Children's Hospital of Boston, tracked more than 1,300 mothers and their children during the study. Mothers were surveyed about breastfeeding at 6 months and 12 months respectively. Children perform standardized intelligence tests at ages 3 and 7. The results showed that breastfeeding children scored higher in intelligence tests on the premise that other factors that could affect children’s intelligence (such as maternal IQ) were controlled.
Many studies suggest that omega-3 fatty acids in fish may play an important role in infant brain development.
Dr. Belfort’s research team also conducted an investigation. The results showed that, while breastfeeding, fish intake did not show a major effect on childhood IQ.
"These new findings, including the possibility that more women will be breast-fed for longer periods of time, have been debated for a long time on the topic of the relationship between breast-feeding and intelligence. Although many other benefits of breast-feeding are already evident Including reducing the risk of diarrhea, ear infections, skin eczema, etc. Improving children's cognitive ability and educational performance may provide greater incentives for mothers to breastfeed,†said DimtriChristakis, a pediatrician at Seattle Children's Hospital.
Dr. Christakis is currently writing an editorial for this study. He also mentioned that the significance of raising the score by four points on the level of crowds can not be ignored. The problem in the United States is not that women do not breastfeed but that they do not have enough duration. Many mothers need to return to work after three months and may not be willing to breastfeed in public places. The creation of a work environment suitable for childcare, the inclusion of breast pumps in medical insurance and other measures will make women more receptive to prolonging their breastfeeding time.
Gail Herrine, an obstetrician from Temple University Health System in Philadelphia, also supports the extension of breastfeeding time, he said:
"This new study suggests that independent of parental intelligence and family environment factors, breastfeeding can improve or improve a child's intelligence."
MLPA ( Multiplex Ligation-dependent Probe Amplification) method detects multiple copy number changes of genes or loci sites. Nowadays, MLPA is used to check large numbers of hereditary disorders and tumour profiling.Since Dutch Scientist Jan Schouten first invented it, the MLPA method was first published in 2002 'Nucleic Acid Research'. The principle of the MLPA is to apply the specific probe design targeting a region of interest on each sample DNA. MLPA method consists of the following steps:
Denaturation > Hybridization Ligation > PCR MLPA Amplificons Capillary Electrophoresis >Data Analysis
PCR reaction consists of the three steps: denaturation, primer annealing and primer elongation. Those steps of PCR amplification are repeated many times. The fluorescence-labeled primers, which will go through the capillary electrophoresis to pass a detector, are incorporated into the size of the amplification products. The measured fluorescence was visualized as a peak pattern, the so-called electropherogram. The raw data from the capillary electrophoresis analyzer forms the input of the MLPA analysis.
The genetic analyzers of Superyears Gene can be used not only for Sanger sequencing but also for fragment analysis. Fragment analysis First, it obtains the fluorescence-labelled DNA fragments, performs the capillary electrophoresis using a Genetic Analyzer and compares the sample's relative size standard with the designed size standard markers through the analysis software.
The genetic analyzer of Superyears Gene can be used in the capillary electrophoresis during the process of the MLPA experiment, and the data obtained can be used for (compatible) professional analysis software.
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