Fingertip blood collection! Minute diagnosis of meningitis
September 01, 2016 Source: Inspection World Network
Window._bd_share_config={ "common":{ "bdSnsKey":{ },"bdText":"","bdMini":"2","bdMiniList":false,"bdPic":"","bdStyle":" 0","bdSize":"16"},"share":{ }};with(document)0[(getElementsByTagName('head')[0]||body).appendChild(createElement('script')) .src='http://bdimg.share.baidu.com/static/api/js/share.js?v=89860593.js?cdnversion='+~(-new Date()/36e5)];Meningitis refers to diffuse inflammatory changes in the pia mater. Common symptoms are fever, headache, vomiting, loss of appetite, and poor mental health.
Bacterial, viral, fungal, spirochetes, protozoa, rickettsia, tumors and leukemia, and other biological pathogenic factors can cause meningitis in violation of the pia mater and spinal cord membrane. Among them, bacterial meningitis is a particularly serious disease. It needs timely treatment. If the treatment is not timely, it may die within a few hours or cause permanent brain damage.
However, the only way to clarify the infection at present is that there has been little change in the past 100 years, that is, the observation of bacteria in the blood is a process that takes 48 hours.
Once a child is diagnosed with a bacterial infection by a doctor, there is no doubt that the child will be taken to the hospital immediately and enter a large amount of antibiotics, aiming to clear the bacteria for the first time. However, every year, countless children are misdiagnosed as viral infections and sent home, and parents give them paracetamol or a lot of boiled water on the advice of a doctor.
Only when the symptoms are not good enough to go to the hospital again, will you find that you have sepsis or meningitis in children, but it is too late to miss the best treatment opportunity.
It is estimated that about 20% of children have fever every year. However, the causes of fever in children are very complicated. Sometimes it may be a fatal infection. Sometimes it may be just a virus invasion. Sometimes it is even medically impossible to diagnose. s reason.
Recently, scientists have made major breakthroughs in the rapid diagnosis of childhood sepsis and meningitis. According to the report in JAMA: Experts can take a small drop of blood from the tip of the finger to determine whether it is infected by a deadly bacteria.
It is reported that the diagnosis can help doctors diagnose whether a child has suffered from a serious bacterial infection, or a cold or flu virus. It will enter the UK National Health Security System (NHS) within five years and is expected to save hundreds of children's lives.
The team of professors at the Imperial Hospital, the head of the study, Professor Michael Levin, found that the body's immune system responds differently to different bacterial infections and viruses. He collected blood samples from 240 infants (2 months to 6 years old) from doctors from the United Kingdom, Spain, and Hollywood in the United States. These samples were all from hospitals.
The scientists analyzed their immune system and scanned 48,000 genes that caused any minor changes. Finally, they identified two genes on the white blood cells and found that mutations only occurred when the bacteria invaded, but not when the virus invaded.
Currently, any single gene marker can be tested, but the diagnosis of these two genes has not yet been released. Therefore, Professor Levin emphasized that the research needs more work to continue.
However, he added, no accident, the diagnosis will be available within 5 years.
Diagnostics come out to help reduce the abuse of antibiotics
The more antibiotics are used, the more susceptible the bacteria are to drug resistance, so that the emergence of superbugs makes antibiotics ineffective.
It is understood that in 2050, the global death crisis caused by antibiotics will exceed cancer.
Professor Jethro Herberg, co-author of the study, said that a useful diagnostic method was developed to reduce the abuse of antibiotics.
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