Russian scientists discover that biological cells can transmit more than 2 bits of information
July 20, 2018 Source: Ministry of Science and Technology
Window._bd_share_config={ "common":{ "bdSnsKey":{ },"bdText":"","bdMini":"2","bdMiniList":false,"bdPic":"","bdStyle":" 0","bdSize":"16"},"share":{ }};with(document)0[(getElementsByTagName('head')[0]||body).appendChild(createElement('script')) .src='http://bdimg.share.baidu.com/static/api/js/share.js?v=89860593.js?cdnversion='+~(-new Date()/36e5)];Research by Russian and Swiss scientists has found that living organism cells can transmit up to 2 bits of information. The research results were published in the journal Nature Communications.
G-protein coupled receptors are currently the target of half of modern drugs. Therefore, it is important to understand the amount of information that cells can reliably receive through these receptors. Experiments conducted by experts in the Department of Pharmacology and Pharmacy, Faculty of Biomedical Sciences, Far Eastern Federal University, Russia, using biological information and computer modeling methods. They applied different concentrations of chemical signals to the cells and recorded the responses of the cells. By repeatedly stimulating muscarinic receptors, scientists have demonstrated that G-protein coupled receptors are capable of transmitting at least 2 bits of information by measuring the calcium response of individual cells. This value is much higher than previously thought, meaning that cells can reliably distinguish between at least four levels of agonists (ie, chemicals that trigger receptor responses).
The researchers pointed out that the above findings solve a mystery that has long plagued the biology community: the principle of signal transmission within cells. The results of the experiment will benefit all those involved in medical research and drug development.
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