Release date: 2017-11-06
A group of biologists at Cornell University in New York printed a miniature artificial small intestine that helps researchers better understand the effects of bacteria on the gut and the body's immune system.
Using AutoCAD Inventor, Stratasys Objet30 Pro 3D printers and Stratasys VeroClear RGD810 3D printing materials, the researchers succeeded in creating a synthetic "small intestine" bioreactor that accurately mimics human intestinal function.
This 3D printed micro-sized small intestine mimics the surface topography of the human gut and the fluid flow required for epithelial cell growth, reproduction and function. According to reports, previous intestinal models failed to accurately reproduce fluid flow.
3D printing of the small intestine (left) promotes mucus production and produces healthier cells
“The gut is where most of our immune system is located and where all our nutrients are absorbed. Therefore, as human beings, the gut is the core of our interaction with the outside world,†the researchers said.
Using the new 3D printed bowel system, researchers can carefully examine fluid flow in the gut. Studies of the 3D printed intestine have shown that after rebuilding the peristaltic flow in the model, the cells can grow as if they were in the true intestine. With this outstanding fluid system, researchers can also study bacterial population dynamics in the gut.
3D printing has proven to be particularly useful for scientists at Cornell University because it allows them to precisely control cell types, nutrients and gas exchange.
Their research has been published in the Nature Journal Scientific Reports.
Source: Tiangongshe
Vitamins are a type of trace organic substances that humans and animals must obtain from food in order to maintain normal physiological functions. In terms of physiological functions, vitamins are neither a raw material for tissues nor a substance for supplying energy, but they are an indispensable substance for the body. It has many types and different chemical structures. Most of them are the components of the coenzyme (or prosthetic group) of certain enzymes. They are the indispensable compounds for maintaining the normal growth (growth, health, reproduction and production function) of the body. It plays a catalytic role in the body to promote the synthesis and degradation of major nutrients (proteins, fats, carbohydrates, etc.), thereby controlling metabolism. Vitamins are essentially low-molecular organic compounds. They cannot be synthesized in the body, or the amount synthesized is difficult to meet the needs of the body, so they must be supplied from the outside. The daily requirement of vitamins is very small (usually measured in milligrams or micrograms). They are neither a raw material for body tissues nor a substance for energy supply in the body. However, they do not regulate material metabolism, promote growth and development, and maintain physiological functions.
Vitamin K2 MK-7, Vitamin C, Vitamin E, Vitamin K2, Vitamin H, Vitamin D3
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