In situ recurrence and metastasis after tumor surgery can effectively prevent
January 24, 2019 Source: Science and Technology Daily
Window._bd_share_config={ "common":{ "bdSnsKey":{ },"bdText":"","bdMini":"2","bdMiniList":false,"bdPic":"","bdStyle":" 0","bdSize":"16"},"share":{ }};with(document)0[(getElementsByTagName('head')[0]||body).appendChild(createElement('script')) .src='http://bdimg.share.baidu.com/static/api/js/share.js?v=89860593.js?cdnversion='+~(-new Date()/36e5)];Recently, from the Changchun Institute of Applied Chemistry of the Chinese Academy of Sciences, the team of researchers, Huang Yubin and Zhou Dongfang, a team of associate researchers, designed a sandwich structure fiber/sponge complex that is very close to clinical application and has both in situ chemotherapy and hemostasis. This complex can be used as a material for in situ implantation after tumor surgery, effectively preventing tumor recurrence and metastasis.
The sandwich structure fiber/sponge complex, as its name suggests, looks like a sandwich: firstly, PLGA/gelatin nano-electrospun fiber loaded with the anticancer drug cisplatin is prepared by electrospinning, and then the fiber is sandwiched in gelatin/ Between the chitosan gel solutions, after lyophilization, a sandwich structure fiber/sponge complex is obtained.
After the sandwich fiber/sponge complex is implanted into the tumor site in situ, the outer sponge can quickly and effectively stop the blood and absorb the tumor cells that are lost during the operation. At the same time, the inner nano-electrospun fiber can be long. The effect of slow release of cisplatin, continuously killing the detached tumor cells adsorbed in the sponge and the tumor cells remaining in the surgical margin, thereby achieving excellent prevention of in situ recurrence, especially distal metastasis." Huang Yubin said.
According to reports, this fiber / sponge composite is a very good ductile material, easy to fold for bleeding sites, especially bleeding sites that are not easily accessible. After in vitro and in vivo hemostasis experiments showed that its hemostatic effect was significantly better than the commercially available medical gelatin sponge. The compound can effectively prevent the recurrence and distant metastasis of the tumor, and can also avoid the administration and treatment of high toxic side effects, significantly increase the compliance of the patient, and is close to the relevant operation of clinical tumor treatment. Good clinical application prospects.
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The energy can flow through the body and interact with damaged cells in many parts of the body operating more like a vitamin that goes where it needs to go. This wavelength is also best for treating the lymph system and acupuncture points. Whereas studies show near-infrared wavelengths in the 850 nm penetrate deeper through skin and bone for relief of chronic pain.
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