Deep exploration: a poor living environment accelerates the degradation of human DNA quality

According to the Shenguo family, the largest overseas medical service institution in China, a study by the Proceedings of the National Academy of Sciences (PNAS) examined the telomeres of the poor, middle-class black, white and Mexican residents of Detroit, and found pressure. It may leave a lasting and destructive mark on the genes of the urban poor. The results show that the poor are not only under pressure, but the DNA quality is also degraded, which once again confirms Darwin's theory of evolution of "the natural survival of the fittest."

Deep exploration: a poor living environment accelerates the degradation of human DNA quality

On May 11th, the British "Daily Mail" website published an article entitled "Scientists say the quality of the poor DNA is degrading" said that stress may leave a lasting and destructive mark on the genes of the urban poor. The article is based on a research paper published in the Proceedings of the National Academy of Sciences (PNAS) on May 3. The study claims that as a result of the hardships of growth, the quality of the DNA of the poor is deteriorating, that is, the telomeres of people living in a poor environment, the DNA sequences that usually shorten with age, are shorter than those with better living conditions. .

Deep exploration: a poor living environment accelerates the degradation of human DNA quality

Douglas A. Granger of the Johns Hopkins School of Public Health and others studied the telomeres of the poor, middle-class black, white, and Mexican-born residents of Detroit.

What is telomere?

Deep exploration: a poor living environment accelerates the degradation of human DNA quality

Telomeres are small pieces of DNA-protein complexes present at the ends of linear chromosomes of eukaryotic cells. Together with telomere-binding proteins, they constitute a special "hat" structure that maintains chromosome integrity and controls cell division cycles. Telomeres and centromeres and origin of replication are the three major elements of chromosome integrity and stability, and the human genome is contained within the chromosome.

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