Release date: 2017-03-13
The reporter learned from Tianjin University on the 8th that the micro-technical team of the School of Fine Arts has made an important breakthrough in the direction of cell-targeted drug introduction. It is the first time in the world to propose the application of micro-electromechanical systems (MEMS) thin-film resonators to excite ultra-high ultrasonic waves. Megahertz's new technology for "targeted cell drug introduction", "surgery for cells."
The technology realizes the precise introduction of a variety of molecules to cells, and provides a new method for the traditional targeted drug introduction technology, expanding the application of MEMS technology in life sciences.
It is reported that the relevant research results of Tianjin University have recently been published online in the internationally authoritative academic journal "Small" in the field of micro-nano technology.
The accurate and efficient introduction of exogenous molecules such as target drug molecules, therapeutic genes and proteins into the interior of cells is an important technology in modern precision medicine and cell molecular biology research. Traditional cell introduction relies on chemical drugs or electrical stimulation, such as "chemotherapy", which not only fails to introduce selective drugs, but also causes "cell immune response", destroying healthy cells and causing large side effects. The micro-nano device has the advantages of small volume and low power consumption, and can be implanted into the body to realize selective cell drug introduction. The use of micro-nano technology to realize single-cell drug introduction has become a hot spot in modern molecular biology research.
Microelectromechanical systems (MEMS) are microelectromechanical systems consisting of movable elements ranging in size from 0.5 to 500 microns. The micro-technical team of Tianjin University, under the leadership of Prof. Pang Wei, a national expert of thousands of people, and the team members of the National Youth Thousand Experts, Professor Duan Xuexin and Associate Professor Wang Yanyan, carried out a large number of microelectromechanical resonators, sensors and actuators research and life. The extension of science and other fields has achieved a number of high-level scientific research results with independent intellectual property rights.
"Application of microelectromechanical systems (MEMS) thin film resonators to stimulate 'extra high-frequency (gigahertz)' for targeted cell drug introduction" technology is the research team to generate "extra high-frequency ultrasound" through resonator excitation, using "extra high-frequency ultrasound" The vibration efficiently and stably forms small holes in the cell membrane, and induces foreign substances such as targeted drugs or gene molecules to enter the cells. The ultra-high ultrasonic wave pressure on the cell membrane is about 60 times that of the general ultrasonic wave, and the cell membrane can be more uniformly stressed, thereby realizing the controllable and precise introduction of the foreign substance into the cell and the nucleus, and has no toxic side effect on the cell itself.
Source: China News Network
Fenbendazole is an organic compound, which is white or almost white powder, odorless and tasteless. This product is soluble in dimethyl sulfoxide, slightly soluble in methanol, insoluble in water, and soluble in glacial acetic acid, with low toxicity. It is a broad-spectrum benzimidazole insect repellent, effective on gastrointestinal parasites. Fenbendazole is a kind of benzimidazole insecticide. It not only has high repellent activity to adult and larva of gastrointestinal nematode, but also has good effect on reticulum, Fasciola and tapeworm. It also has strong egg killing effect.
Fenbendazole is a broad spectrum benzimidazole anthelmintic used against gastrointestinal parasites including roundworms,hookworms, whipworms, the taenia species of tapeworms, pinworms, aelurostrongylus, paragonimiasis, strongylesand strongyloides and can be administered to sheep, cattle,horses, fish, dogs, cats, rabbits and seals.
Note: Don't use with bromsalan flukicides such as dibromsalan and tribromsalan.
Product Name
Wholesale Price Veterinary Medicine Powder 99% Fenbendazole
Appearance
White crystalline powder
Molecular formula
C15H13N3O2S
Assay
99%
Shelf Life
24 months when properly stored
Storage
Keep in a cool, dry, dark location
For sheep:
For cattle:
For horse:
For pig:
For dog & cat:
For wildlife:
Deer and other birds of prey.
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It is efficient for treating imageo and larva of haemonchosis, ostertagia, trichostrongyle, cooperia, nematodirus, trichuris and dictyocaulus. It has good effec in treating moniezia expansa and M.benedeni. It needs large dose for trematode.
The expelling spectra of cattle is almost similar to that of sheep, need large dose for trematode. It has good effect in treating imago of fasciola hepatica and schistosomula of bovine paramphistomum.
It has good effect in treating parascaris equorum, imago and larva of oxyuris equi, Pprobstmayria vivipara, strongylus vulgaris.
It has good expelling parasite effect in treating imago and larva of ascaris suum, hyostrongylus rubidus, and oesophagostomum.
It has obvious effect in treating ancylostoma caninum, trichuris, and roundworm of dog. Also is effect in treating roundworm, hookworm and tapeworm of cat.
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Furazolidone Powder,Levamisole Hydrochloride,Albendazole Powder,Fenbendazole Powder
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