Guangzhou Hospital isolated virus strain from the urine of Zika patients

Release date: 2016-03-02

On February 29th, Guangzhou Eighth People's Hospital revealed that the collaborative innovation team of the hospital successfully isolated Zika virus strains from the urine of Zika virus patients.

As the designated hospital for major infectious diseases in Guangdong, since the first case of imported Zika virus infection in Guangdong on February 12, the Eighth People's Hospital of Guangzhou cooperated with the Institute of Microbiology and Epidemiology of the Academy of Military Medical Sciences of the People's Liberation Army and the Entry-Exit Inspection and Quarantine Bureau. Joint research, the first successful separation of two Zika virus in China on the 25th.

"One of the two strains of virus originated from the urine samples of patients who entered Guangzhou from Venezuela, and the other strain was derived from the blood samples of patients who entered Shenzhen from Samoa," said Yin Chibiao, dean of the Eighth People's Hospital of Guangzhou.

Researchers say that patients with Zika virus infection have a very short viremia period, which poses a great challenge to the traditional virus isolation work. Zhang Fuchun, deputy head of the Zhaika virus disease clinical expert group in Guangdong Province, said that obtaining the whole genome sequence of the virus is like the police found the DNA evidence of the “criminal” from the crime scene, and the virus strain was isolated, just like the police seized it. "Live target" is quite difficult, especially for separating the virus directly from the patient's urine specimen for the first time in the world.

Source: Jinghua Times

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